The problem with experimentation
Years ago it was recognised that regulatory studies had to be normalised to prevent inappropriate measurements from being made and to provide a basis for scientific methodology allowing results from different substances to be compared. International Chemical testing Guidelines (e.g. ISO, OECD) were created for this purpose but every substance has its own set of properties and all potential issues cannot be covered in just a few pages.
An introduction to QSAR
The term “QSAR” stands for Quantitative Structure-Activity Relationship.
QSARs are based on the principle that similar chemical structures can lead to similar biological activities. QSAR is often replaced by the term ‘QSPR’ (Quantitative Structure-Property Relationship).